Mayo Clinic Hospital Rochester in Rochester, MN
Also known as Mayo Clinic Saint Marys Campus
In a medical emergency, call 911. This page is for information only.
About Mayo Clinic Hospital Rochester
Mayo Clinic Hospital Rochester is an acute care hospital in Rochester, Olmsted County, Minnesota. It reports its ownership to Medicare as nonprofit (church-affiliated). It provides emergency services. It is listed as a Level I adult, Level I pediatric trauma center. Its CMS Overall Hospital Quality Star Rating is 5 out of 5. It has 2,059 licensed beds, according to state license data via HIFLD. CMS also lists an inpatient rehabilitation unit inside the hospital. It meets the CMS Birthing-Friendly designation criteria for maternity care. Mayo Eugenio Litta Children's Hospital is on the same campus or next door.
Quality ratings
How this hospital compares with the national rate on each measure group:
Source: Centers for Medicare & Medicaid Services, Hospital General Information. How star ratings work.
Emergency room times
Lower times are better. Reporting period ending September 2025. Source: CMS Timely and Effective Care. What these numbers mean.
Infections and sepsis care
- MRSA bloodstream infectionsBetter than national · SIR 0.15
- Catheter-associated urinary tract infections (CAUTI)Better than national · SIR 0.63
- Clostridioides difficile (C. diff) infectionsBetter than national · SIR 0.56
- Central line bloodstream infections (CLABSI)Better than national · SIR 0.41
- Surgical site infections after abdominal hysterectomyNo different · SIR 1.08
- Surgical site infections after colon surgeryNo different · SIR 0.72
42% of patients with severe sepsis or septic shock received all the recommended early care steps (SEP-1). Higher is better.
SIR is the standardized infection ratio: below 1 means fewer infections than predicted for a hospital like this one. Period ending September 2025. Source: CMS Healthcare-Associated Infections and Timely and Effective Care.
What patients say
- Patient survey star rating
- Would definitely recommend89%
- Rated the hospital 9 or 1085%
- Completed surveys4,221
Survey period ending September 2025. Source: CMS HCAHPS Patient Survey.
Map
44.02157, -92.48167
Nearby hospitals
- Mayo Eugenio Litta Children's HospitalRochester, MNChildren's hospitalSame campus
- Olmsted Medical Center1650 Fourth Street Southeast, Rochester, MN · Level IV traumaAcute care hospital2.0 mi
- Community Behavioral Health Hospital Rochester251 Wood Lake Drive Southeast, Rochester, MNPsychiatric hospital3.6 mi
Frequently asked questions
Where is Mayo Clinic Hospital Rochester located?
Mayo Clinic Hospital Rochester is at 1216 Second Street Southwest, Rochester, MN 55902 in Olmsted County.
Does Mayo Clinic Hospital Rochester have an emergency room?
Yes. Mayo Clinic Hospital Rochester reports emergency services to Medicare, and patients spent a median of 246 minutes in its emergency department before leaving. In a life-threatening emergency, call 911.
What is the CMS star rating of Mayo Clinic Hospital Rochester?
Mayo Clinic Hospital Rochester has a CMS Overall Hospital Quality Star Rating of 5 out of 5. The rating combines measures of mortality, safety of care, readmission, patient experience and timely and effective care, compared with hospitals nationwide.
Is Mayo Clinic Hospital Rochester a trauma center?
Yes. It is listed as a Level I adult, Level I pediatric trauma center in the HIFLD hospitals data, which is compiled from state trauma registries (source date April 2024). Trauma designations are renewed periodically, so confirm with the Minnesota EMS or trauma program. In an emergency, call 911: paramedics take seriously injured patients to the right trauma center.
What is the phone number of Mayo Clinic Hospital Rochester?
The main phone number on record with Medicare is (507) 255-5123.
Would patients recommend Mayo Clinic Hospital Rochester?
In the most recent HCAHPS patient survey (4,221 completed surveys), 89% of patients said they would definitely recommend the hospital, and 85% rated it 9 or 10 out of 10.
Related guides
- How CMS Hospital Star Ratings WorkThe five measure groups behind the 1 to 5 star Overall Hospital Quality Star Rating, how it is calculated and what it leaves out.
- How to Choose a HospitalA practical checklist for planned care: insurance networks, procedure volume, quality ratings, certifications and cost estimates.
- Hospital Financial Assistance and Charity CareHow IRS 501(r) rules work, who usually qualifies for free or discounted care, and how to apply step by step.
- How to Choose a Hospital to Give BirthLevels of maternal and newborn care, the CMS Birthing-Friendly designation, quality data and questions to ask on a tour.